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Thin basement membrane disease
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Thin basement membrane disease : ウィキペディア英語版
Thin basement membrane disease

Thin basement membrane disease (TBMD, also known as ''benign familial hematuria'' and ''thin basement membrane nephropathy'') is, along with IgA nephropathy, the most common cause of asymptomatic hematuria. The only abnormal finding in this disease is a thinning of the basement membrane of the glomeruli in the kidneys. Its importance lies in the fact that it has a benign prognosis, with patients maintaining a normal kidney function throughout their lives.
==Signs and symptoms==
Most patients with thin basement membrane disease are incidentally discovered to have microscopic hematuria on urinalysis. The blood pressure, kidney function, and the urinary protein excretion are usually normal. Mild proteinuria (less than 1.5 g/day) and hypertension are seen in a small minority of patients. Frank hematuria and loin pain should prompt a search for another cause, such as kidney stones or loin pain-hematuria syndrome. Also, there are no systemic manifestations, so presence of hearing impairment or visual impairment should prompt a search for hereditary nephritis such as Alport syndrome.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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